Such is the case with magnesium glycerophosphate. If the magnesium is chelated with the right compound, however, it is protected from forming a hydration shell, which also improves its absorption. It becomes surrounded by water molecules completely by what is referred to as a “hydration shell.” In fact, magnesium alone can hold so much water that the radius of the hydrated magnesium cation is about 400 times larger than its dehydrated radius.5 This creates a roadblock in absorption and is the reason that some magnesium salts have laxative effects. Consequently, these compounds can have low bioavailability, and the magnesium can be eliminated as waste before absorption into the bloodstream.įurthermore, when magnesium is in its dissolved state, it has an extreme attraction for molecules of water. However, magnesium salts commonly used in supplementation begin to drop in solubility with the more alkaline pH of the intestines. On the other hand, once it reaches the intestinal tract, you want magnesium to be soluble so that it can be absorbed.
BEST FORM OF MAGNESIUM FOR PVCS FREE
The reason is that this reaction means that the magnesium is free to bind with other ions in the stomach, creating insoluble compounds.4 While soluble magnesium sounds like a good thing, that’s not the case when it’s in the stomach. In passing through the stomach, magnesium compounds can react with stomach acid, creating salts such as magnesium chloride, which are totally soluble at this acidic pH. Magnesium Glycerophosphate Absorption and Tolerability In fact, one molecule of glycerophosphate can be used to produce 19 molecules of ATP after passing through the Krebs cycle.3 Of course this is only meaningful if magnesium glycerophosphate is well absorbed. Phosphate is the most abundant element in the human body, and phosphate, glycerol and magnesium can be used to help generate ATP. Once the glycerophosphate is cleaved off of the magnesium in the body, not only is the magnesium available for use, but so is the phosphate and the glycerol. In the case of magnesium glycerophosphate, magnesium is attached to glycerol and phosphoric acid (i.e. All forms of magnesium used in dietary supplements provide one or more magnesium salts. Minerals attached to acids are called mineral salts. Rather it is attached to some type of organic or inorganic acid. Magnesium doesn’t naturally exist by itself. population does not meet the recommended dietary allowance (RDA) for levels of Mg.2 Consequently, there is a good case for magnesium supplementation-and magnesium glycerophosphate is a good choice for this purpose. The conduction of nerve impulses, muscle contraction, normal heart rhythm, cell signaling and cell migration, which may be important in wound healing, are also all magnesium-dependent activities.1Īlthough overt magnesium (Mg) deficiency is not common in healthy individuals who are consuming a balanced diet, the United States Department of Agriculture, Agricultural Research Service, has reported that 57 percent of the U.S. Magnesium is also required for transporting potassium and calcium ions across cell membranes. In addition, magnesium is required for the synthesis of nucleic acids, proteins, carbohydrates, lipids and the antioxidant glutathione. It is needed for more than 300 metabolic reactions, including magnesium-dependent chemical reactions required to metabolize carbohydrates and fats in the production of adenosine triphosphate (ATP), the “energy currency” of the body. This includes a structural role in bone, cell membranes, and chromosomes. Magnesium is an essential mineral with multiple functions in the human body. Specifically, I’m referring to magnesium glycerophosphate-but before I begin, let’s do a quick background review about magnesium’s functions and its adequacy in our diet. I found the research on one of those forms to be so interesting, that I thought it was worthy of a new magnesium article. In the five years since then, I’ve had the opportunity to read quite a few new studies about various forms of magnesium. Back in 2013, I wrote a general article about magnesium for Vitamin Retailer.
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